The Journal of American Medical Science and Research

1.0 Introduction Sickle cell anaemia (SCA) is one of the most common inherited haemoglobin disorders globally and remains a major public health challenge, particularly in sub-Saharan Africa, where the burden

Clinician Perspectives on the use of Rabeprazole in the Management of Gastroesophageal reflux disease in Indian Settings

Introduction Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal disorders globally and continues to impose a substantial clinical and public health burden. In 2021, an estimated 825.60

Association between Bacterial Virulence Factors and Host Immune Response: An Updated Review

1. Introduction Bacterial infections remain a significant cause of morbidity and mortality worldwide, particularly in developing regions where infectious diseases continue to impose a heavy healthcare burden. The pathogenesis and

Awareness, Knowledge and Perception of Sickle Cell Anaemia Among Adolescents in Selected Private Secondary Schools in Port Harcourt, Rivers State, Nigeria

GSK3β (rs334558) Promoter Polymorphism and Susceptibility to Breast Cancer: Case-Control Study in a South Indian Population with Comprehensive Statistical Analysis

Introduction Glycogen synthase kinase-3 beta (GSK3β; OMIM #605004) is one of those enzymes whose full significance in biology only became clear long after its initial discovery. Originally characterised as a

Association of Iron Deficiency Anemia with the Development and Progression of Heart Failure

Introduction Heart failure (HF) is a prevalent and growing condition, with its burden expected to increase by up to 50% by 2030 due to population ageing and improved survival

The Impact of Heart Disease on Maternal and Fetal Outcomes in Pregnancy

Introduction Cardiovascular disease (CVD) complicates 1% to 4% of pregnancies and remains a leading cause of non‑obstetric maternal morbidity and mortality worldwide [1]. Its incidence is rising due to

The seroprevalence of human CMV among children aged 1-5 years

The Herpesviridae family of viruses includes human cytomegalovirus (CMV), which is always present but only affects certain people. The organism has a large double-stranded DNA genome of 236 kb

Interleukin-33 (IL-33) Profile in Toxoplasma gondii-Seropositive and Seronegative Pregnant Iraqi Women

Introduction The apicomplexan parasite Toxoplasma gondii infects a substantial portion of the global population. While immunocompetent individuals typically experience an asymptomatic or mild infection, the acquisition of T. gondii during pregnancy presents a

Journal of American Medical Science and research