Given the absence of a Greek neoplasm registry, this study aims to develop a logical systematic algorithm for the identification of newly diagnosed cancer patients (incidence) within a specified timeframe. Specifically, it focuses on four distinct cancer types, namely breast, lung, colon, and prostate cancer, for the year 2017. This alternative methodological approach leverages administrative datasets, particularly healthcare service records pertaining to cancer patients as documented by Greek Social Security Funds’s perspective.