Liquid biopsy

An Overview of the current state of cancer diagnosis and treatment in sub-Saharan Africa

  • Umobong EO1
  • Ugwu IV2
  • Gbaa ZL3
  • Ojo BA2
  • Uko AF4
  • Onyewuchi AJ5
  • Gbaa AF6

Introduction The global burden of cancer is rising, with low- and middle-income countries (LMICs), particularly in SSA, bearing an increasing share1. While cancer incidence in SSA is currently lower than in high-income regions, mortality rates are significantly higher, reflecting profound disparities in access to timely diagnosis and effective treatment2,3. Projections indicate a near doubling of … Read more

Unveiling the Timeline of Liquid Biopsy Analytes Release: Review of the Implications for Early Cancer Detection

  • Umobong EO1
  • Gbaa ZL2
  • Anenga Rn3
  • Ugwu I4
  • Tsegha LJ5
  • Ojo BA6
  • Gbaa FA7
  • Otene, Sa8

Introduction Cancer remains one of the leading global causes of morbidity and mortality, with an estimated 19.3 million new cases and 10 million deaths reported in 2020 alone [1]. Despite advances in therapeutics, survival outcomes are largely determined by the stage at diagnosis, highlighting the critical importance of early detection. Conventional diagnostic approaches, such as … Read more

Liquid Biopsy: A Review of Non-Invasive Frontier in Cancer Diagnosis and Management

  • Anenga RN1
  • Ugwu IV2
  • Umobong EO3
  • Gbaa ZL4
  • Tsegha LJ5
  • Ojo BA6
  • Gbaa FA7
  • Otene, Sa8

Introduction: With an estimated 19.3 million new cases and almost 10 million deaths in 2020 alone, cancer is still one of the leading causes of death worldwide [1]. Invasive tissue biopsy is the conventional “gold standard” for molecular profiling and cancer diagnosis. Despite its value, this procedure is frequently constrained by its risks, which include … Read more