This study investigated tebuconazole-induced oxidative stress and muscle toxicity in Cyprinus carpio, assessing biochemical, enzymatic, and histopathological parameters. Fish exposed to sublethal TBZ concentrations (6.47 µl/l and 8.09 µl/l) for 30 days showed significant reductions in protein, lipid, SOD, GSH, GPx, LDH, and a biphasic CAT response, alongside elevated free amino acids, GR, and AChE activity, indicating redox imbalance and neuromuscular disruption. Muscle histology revealed progressive degeneration. Propolis supplementation markedly reversed these alterations, restoring biochemical and enzymatic balance and preserving muscle architecture. Findings highlight propolis as a promising intervention against pesticide-induced aquatic toxicity.