Article Archive: Volume 2 Issue 1 2023

Abstract: Alpelisib, a selective inhibitor of the phosphatidylinositol 3-kinase (PI3K) alpha isoform, has emerged as a promising therapeutic option for patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer harboring PIK3CA mutations. This review provides a comprehensive overview of the clinical efficacy and safety profile of alpelisib in the … Read more

Introduction: Chickenpox, caused by the varicella-zoster virus, continues to pose a challenge, especially in household settings where transmission is efficient. This review introduces the concept of using gamma globulin as a strategic intervention to modify the course of the disease in household contacts. We outline the current landscape of chickenpox management, emphasizing the need for … Read more

Introduction: Cancer treatment has undergone transformative changes in recent decades, driven by advances in understanding tumor biology, molecular mechanisms of oncogenesis, and the development of novel therapeutic agents. This comprehensive review aims to provide an up-to-date overview of current perspectives in cancer treatment, highlighting the diverse modalities and emerging strategies that have revolutionized oncology practice. … Read more

Introduction: The modern world is rife with stressors, ranging from everyday challenges to global crises, and understanding the multifaceted nature of stress is crucial. Stress acts as a pervasive force, influencing physiological responses and acting as a precursor to various health conditions. As we embark on this exploration, we aim to unravel the mechanisms that … Read more

The COVID-19 pandemic has not only reshaped our daily lives but has also spurred a global scientific endeavor to understand the intricacies of the virus-host interaction. At the forefront of this exploration is the examination of how the immune system responds to the SARS-CoV-2 virus and the consequential effects on human health. This comprehensive review … Read more