Original Research Article

Knowledge, Attitude and Practice Survey on Awareness, Risk Factors, Screening and Prevention of Cervical Cancer among Women in India

  • Khyati Bajaj1
  • Deepal Singh1
  • Mohammad Umar Atique11
  • Mohd. Arfat2

Introduction Cervical cancer remains a major public health challenge worldwide, particularly affecting women in low- and middle-income countries. It is the fourth most common cancer among women globally, with approximately 570,000 new cases and 311,000 deaths annually. India bears a substantial proportion of this burden, reporting nearly 96,000–120,000 new cases each year {1}. Although incidence … Read more

Histopathological Patterns of Inflammatory and Eczematous Dermatoses in Abuja, Nigeria: A 10-Year Retrospective Study

  • Umobong EO1
  • Gbaa ZL2
  • Ojo BA3
  • Udo ME4
  • Udo ME4

Introduction Inflammatory dermatoses are a mixed bag of non-cancerous skin conditions that often look alike, both to the naked eye and under the microscope. This group spans spongiotic (eczematous) reactions, psoriasiform changes, lichenoid or interface patterns, vesiculobullous disease, vasculitis, granulomatous inflammation and panniculitis [1]. Eczematous conditions in particular are marked by spongiosis, fluid building up … Read more

A prospective observational study Evaluating antibiotic utilization and prescribing practices among hospitalized patients

  • Syeda Mohammadi
  • Mohammed Avez Ali
  • Israr Uddin

INTRODUCTION ANTIBIOTICS Antibiotics are chemical substances used to treat infections caused by bacteria. They may either kill bacteria (bactericidal) or inhibit their growth (bacteriostatic)1,3,4,5. Antibiotics are among the most important discoveries in modern medicine and are widely used in general medical practice for treating infections such as respiratory tract infections, urinary tract infections, gastrointestinal infections, … Read more

Histopathological Spectrum of Lichenoid and Interface Dermatoses: A Ten-Year Retrospective Study from Abuja, Nigeria

  • Umobong E1
  • Gbaa ZL2
  • Ojo BA3
  • Udo ME4
  • Eddy AN4

Introduction Lichenoid and interface dermatoses are a diverse group of inflammatory skin disorders that share a characteristic pattern of injury at the dermoepidermal junction rather than a single underlying cause. Histologically, interface dermatitis is characterised by basal keratinocyte injury and apoptosis, usually with a lymphocytic infiltrate along the dermoepidermal junction and variable pigmentary incontinence. These … Read more

Demographic and Histopathological Profile of Skin Biopsies at a Private Laboratory in Abuja, Nigeria: A 10-Year Retrospective Study

  • Umobong E1
  • Gbaa ZL2
  • Ojo BA3
  • Udo ME4
  • Eddy AN4

Introduction Skin diseases constitute a substantial global public health burden, contributing significantly to morbidity and the demand for dermatological services {1}. In sub-Saharan Africa, accurately characterizing this burden remains challenging because of socioeconomic disparities, environmental factors, and limited access to specialized dermatological and dermatopathological services {2,3}. Although many dermatological conditions can be diagnosed and managed … Read more

Histopathological Profile of Psoriasiform Disorders in Abuja, Nigeria: A Ten-Year Review

  • Umobong E1
  • Gbaa ZL2
  • Ojo BA3
  • Udo ME4
  • Eddy AN4

INTRODUCTION Psoriasis is a chronic, immune-mediated inflammatory skin disorder characterised histologically by a psoriasiform reaction pattern, including epidermal hyperplasia, parakeratosis, and dermal inflammatory infiltrates {1}. It affects an estimated 125 million people globally, with prevalence varying markedly by geography and ethnicity, ranging from under 0.1% in parts of East Asia to over 4% in Scandinavian … Read more

Synthesis, Characterization and Biological Evaluation of Some New Methylxanthine-Bearing Chalcone Derivatives as Antiproliferative agents

  • Valarmathy Joshua1
  • L. Samuel Joshua1
  • Sherlyn Joshua2
  • Vinolyn Joshua2

1. Introduction Chalcones are an important class of open-chain flavonoids chemically known as 1,3-diphenyl-2-propen-1-ones, in which two aromatic rings are connected through a three-carbon α,β-unsaturated carbonyl framework. Their characteristic structure contains a ketoethylenic moiety (–CO–CH=CH–) that serves as a highly reactive pharmacophoric unit responsible for many of their biological activities. The presence of conjugated double bonds … Read more

D-Dimer level as a diagnostic marker in neonatal sepsis

  • Kahtan Adnan Kamel1
  • Nihad Khalawe Tektook2
  • Mohammed Flayyih Tareef3
  • Shams Al-Mundhader Saad Abd4
  • Manhal Saad Abd5

Introduction    Neonatal sepsis remains a formidable challenge in perinatal medicine, contributing significantly to neonatal morbidity and mortality worldwide. Its diagnosis is particularly difficult due to the non-specific and often subtle clinical signs in newborns, which can overlap with non-infectious conditions. Blood culture, the historical gold standard, is hindered by a 24–48-hour time delay and … Read more

Clinician Perspectives on the use of Rabeprazole in the Management of Gastroesophageal reflux disease in Indian Settings

  • Manjula S
  • Krishna Kumar M

Introduction Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal disorders globally and continues to impose a substantial clinical and public health burden. In 2021, an estimated 825.60 million cases were reported worldwide, corresponding to an age-standardized prevalence rate of 9,838.60 per 100,000 population and 6.34 million disability-adjusted life years, with projections suggesting … Read more

Awareness, Knowledge and Perception of Sickle Cell Anaemia Among Adolescents in Selected Private Secondary Schools in Port Harcourt, Rivers State, Nigeria

  • OZIGBO Chinelo Juliana1
  • OKORIE Elizabeth-Martha2

1.0 Introduction Sickle cell anaemia (SCA) is one of the most common inherited haemoglobin disorders globally and remains a major public health challenge, particularly in sub-Saharan Africa, where the burden of the disease is highest [1,2]. It is the most common and severe form of sickle cell disease (SCD) and results from a genetic mutation … Read more