Osteoarthritis (OA) of the knee is a prevalent degenerative joint disease that affects mobility and balance. This study evaluates clinical analysis of balance deficits in individuals with knee osteoarthritis using the clinical assessment tools and expanded case studies. Tools like the Berg Balance Scale (BBS), Timed Up and Go (TUG) test, Functional Reach Test (FRT), and Activity-Specific Balance Confidence Scale (ABC) were employed. Results showed significant balance deficits in individuals with moderate to severe OA compared to controls, highlighting the need for targeted interventions. Further research is required to explore balance improvement strategies and their long-term impact on functionality.