Cancer

An Overview of the current state of cancer diagnosis and treatment in sub-Saharan Africa

  • Umobong EO1
  • Ugwu IV2
  • Gbaa ZL3
  • Ojo BA2
  • Uko AF4
  • Onyewuchi AJ5
  • Gbaa AF6

Introduction The global burden of cancer is rising, with low- and middle-income countries (LMICs), particularly in SSA, bearing an increasing share1. While cancer incidence in SSA is currently lower than in high-income regions, mortality rates are significantly higher, reflecting profound disparities in access to timely diagnosis and effective treatment2,3. Projections indicate a near doubling of … Read more

Advances in Colorectal Cancer Detection: A Review of Biomarkers, Imaging and Prevention

  • Uko AF1
  • Gbaa LZ2
  • Onyewuchi AJ 1
  • Tsegha LJ 3
  • Otene, SA4

Introduction  Colorectal cancer (CRC) ranks among the primary causes of cancer-related morbidity and mortality worldwide, accounting for an estimated 1.9 million new cases and 900,000 deaths annually {1}. Historically, its incidence has been greater in developed nations; however, recent epidemiological trends reveal an increasing prevalence in low- and middle-income areas, particularly in Sub-Saharan Africa and … Read more

Liquid Biopsy in Oncology: A Review of Global Perspectives, Sub-Saharan African Realities, and Future Innovations

  • Otene, SA 1
  • Ugwu, IV 2
  • Umobong, EO3
  • Gbaa, ZL4
  • Onyewuchi, AJ5
  • Anenga, RN6
  • Ojo, BA7
  • Gbaa, A8

Introduction: Cancer is a leading cause of morbidity and mortality worldwide, with almost 20 million new cases and 9.7 million deaths documented in 2022, signifying a continual rise in occurrence in both wealthy and impoverished areas [1]. Conventional tissue biopsy has proven essential for cancer diagnosis and molecular characterisation; nevertheless, it is inherently invasive, time-consuming, … Read more

Nanostructured Therapeutics in Inflammation-Associated Cancer: From Molecular Design to Clinical Potential

  • Karthikeyan Dakshaa
  • Rajan Radha Rasmi b
  • Kanakaraj Suganyaa
  • Kunnathur Murugesan Sakthivel c
  • Devanesan Sanjeevi Ranjith Santhosh Kumard
  • Sankar Soundariyae
  • Mythili Saravanaf

Introduction Nanoparticles, long before their modern scientific conceptualization, have played a historical role in human culture, appearing in ancient glassware, medicines, and pigments as early as the 9th century [1]. The scientific framework of nanotechnology was formally introduced by Richard Feynman in his 1959 lecture “There’s Plenty of Room at the Bottom”, laying the foundation … Read more

Investigating the possibility of redesigning Oncology patients’ care based on datafrom Social Security administrative sources

  • Christos Priftis1
  • Olga Siskou2,3
  • Dafni Kaitelidou3
  • Theodoros Mariolis4
  • Petros Galanis3
  • Olympia Konstantopoulou3
  • Kostas Mathioudakis5
  • Emmanouil Velonakis6

Cancer consists a major public health problem [1], worldwide and especially in middle and high income countries, including Greece [2]. Therefore, optimal and accurate estimation of cancer incidence is still a challenge. Based on estimates by the Global Cancer Observatory (GLOBOCAN), the most common types in Europe (2018) are breast cancer (ICD-10:C50), colon cancer (ICD-10:C18), … Read more