Article Archive: Volume 5 Issue 1 2026

GSK3β (rs334558) Promoter Polymorphism and Susceptibility to Breast Cancer: Case-Control Study in a South Indian Population with Comprehensive Statistical Analysis

  • Sarika Jarjapu1
  • Shafeen Khan1
  • Santhoshi Nachari1
  • Raghunadha Rao Digumarthi2
  • Vishnupriya Satti3
  • Sandhya Annamaneni1

Introduction Glycogen synthase kinase-3 beta (GSK3β; OMIM #605004) is one of those enzymes whose full significance in biology only became clear long after its initial discovery. Originally characterised as a regulator of glycogen metabolism phosphorylating and inactivating glycogen synthase in response to insulin it is now understood to be a constitutively active kinase operating at … Read more

The seroprevalence of human CMV among children aged 1-5 years

  • Pakiza Fouad Mohammed1
  • Nuha Mumin Wahid 2
  • Dunya Mahmoud Abd Alrahman3
  • Zaid Mohammed Al-Bayati4,5

    The Herpesviridae family of viruses includes human cytomegalovirus (CMV), which is always present but only affects certain people. The organism has a large double-stranded DNA genome of 236 kb that codes for at least 167 gene products. More than 40 of these gene products change the host’s immune response after infection. After the first … Read more

Interleukin-33 (IL-33) Profile in Toxoplasma gondii-Seropositive and   Seronegative Pregnant Iraqi Women

  • Nihad Khalawe Tektook1
  • Eman Ghadban Salih2
  • Batwl Alaa Ameen3
  • Hussein Thumad Alkaisey4
  • Shams Al-Mundhader Saad Abd5

Introduction       The apicomplexan parasite Toxoplasma gondii infects a substantial portion of the global population. While immunocompetent individuals typically experience an asymptomatic or mild infection, the acquisition of T. gondii during pregnancy presents a serious medical challenge. Primary maternal infection can lead to vertical transmission, resulting in congenital toxoplasmosis, which is associated with spontaneous abortion, stillbirth, and severe neurological … Read more

Awareness, Perception and Usage of Artificial Intelligence Tools in Medical Research Among Nigerian Doctors

  • Ushakuma Michael Anenga1
  • Ehi Edwin Eseigbe2
  • Sesugh Matthew Iorfa3
  • Nurudeen Umar4
  • Samuel Okwuchukwu Ilikannu5
  • Yusuf Alfa6
  • Jeremiah Isogun7

Introduction The integration of artificial intelligence (AI) into healthcare and medical research is transforming the landscape of modern medicine [1]. AI, defined as the ability of computer systems to perform tasks that normally require human intelligence, such as learning, reasoning, and problem-solving, is increasingly being used to augment various aspects of clinical practice and biomedical … Read more

Yoga Prana Vidya Healing as a Complementary Approach in Pill-Induced Esophagitis: A Case Report

  • Girija H1
  • Venkata Satyanarayana Nanduri2

Introduction Pill Esophagitis Pill-induced esophagitis (PE) means injury to the oesophagus from medications getting stuck, dissolving, and causing damage, often occurring in the mid-oesophagus. Common causes include certain antibiotics, NSAIDs, bisphosphonates, iron supplements, and potassium chloride, with risk factors like taking pills with inadequate water or while lying down. Symptoms typically include painful or difficult … Read more

Multisystem Biochemical Toxicity in Experimental Rats: Evidence from Hepatic, Renal, Lipid, Oxidative, and Reproductive Indices

  • Eruotor O. Harrison1
  • Chinwebudu M. Melford2

INTRODUCTION Systemic toxicity resulting from chemical exposure, including fluoride compounds known to induce oxidative stress. Organs central to metabolism, detoxification, and excretion, particularly the liver and kidneys, are especially vulnerable, and their dysfunction often precipitates secondary metabolic, electrolyte, and redox imbalances. Alterations in hepatic enzymes, bilirubin fractions, plasma proteins, renal clearance markers, and electrolyte homeostasis … Read more

Ectopic Gastric and Pancreatic Tissue in An Ileal Lipoma-Pathological Rarity Causing Intussusception

  • MG Abhishek1
  • Pravallika J2
  • Vijay Shankar1

INTRODUCTION Derived from the concept of tissue being in “other places,” heterotopia describes the ectopic presence of gastric or pancreatic elements in the gastrointestinal tract [1]. The reported incidence of these anomalies varies significantly in the literature, with autopsy findings citing a frequency between 0.55% and 13.7%. Because heterotopic pancreas (HP) is typically asymptomatic, it is most frequently … Read more

Comparison of Echocardiographic Parameters Between Left Lateral Decubitus Position and Supine Position

  • Wahitha Thahseem Z1
  • M. Rajesh2
  • B. Subashini3
  • S. Andrew John Silvester4

1. Introduction Transthoracic echocardiography (TTE) has evolved as an indispensable non-invasive diagnostic tool for comprehensive cardiac assessment, providing real-time visualization of cardiac structure and function [1]. The cardiovascular system demonstrates remarkable adaptability to gravitational forces and postural changes, with body position influencing venous return, cardiac preload, stroke volume, and ultimately, hemodynamic parameters measurable by echocardiography … Read more

Comparative Analysis of Coronary Angiographic Patterns in Patients with and Without Diabetes: An Observational Hospital-Based Investigation

  • Roonak Hamid Wani
  • Abhishek Gupta
  • Mustafa Bashir

Introduction Diabetes mellitus (DM), particularly type 2, is a major risk factor for coronary artery disease (CAD) and is often considered equivalent to established CAD in terms of cardiovascular risk [1,2]. Globally, diabetes prevalence continues to rise, with significant contributions from India [3-5]. CAD remains a leading cause of mortality, and diabetes accelerates its progression … Read more

Efficacy of Indian Diabetic Risk Score (IDRS) in Predicting Type 2 Diabetes Mellitus Among Adults of Kanpur Nagar, Uttar Pradesh- A Community-Based Cross-Sectional Study

  • Vikas Pal1
  • Tanu Midha1
  • Garima Pal2
  • Santosh Kumar Barman1
  • Sumit Kumar1

INTRODUCTION Globally, lifestyle diseases are becoming more common. With the number of persons with diabetes expected to increase from 537 million in 2021 to 643 million by 2030, T2DM in particular has become a significant global public health concern. They are becoming the leading cause of illness and mortality, surpassing communicable diseases [1]. With 26 … Read more